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Trajectories of Prescription Opioid Dose and Risk of Opioid-related Adverse Events Among Older Medicare Beneficiaries in the United States: A Nested Case–control Study

About the Course

This study aims to compare trajectories of prescribed opioid doses in six months preceding an incident of opioid related adverse events (ORAE), for cases and for a matched control group of older patients with chronic noncancer pain (CNCP). At issue in this study is an improved understanding of patterns of prescription opioid misuse, dependance, and poisoning among patients age 65 and older.

This course is based on the reading-based online article, Trajectories of Prescription Opioid Dose and Risk of Opioid-related Adverse Events Among Older Medicare Beneficiaries in the United States: A Nested Case–control Study created by Yu-Jung Jenny Wei et al. in 2022.

Publication Date:

PLOS Medicine 2022 March; 19(3): e1003947 Mar 2022

Course Material Authors

Course Material Authors authored the material only, and were not involved in creating this CE course. They are identified here for your own evaluation of the relevancy of the material this course is based on.

Yu-Jung Jenny Wei, PhD

Dr. Wei is an assistant professor of pharmaceutical outcomes and policy at the University of Florida College of Pharmacy. Her research focus is on the improvement of pharmacotherapy in geriatric patients. Her work has been published in multiple peer reviewed journals.

Cheng Chen, PhD student

Cheng Chen is a PhD student and teaching assistant at the University of Florida College of Pharmacy. She has published a few works in peer reviewed journals.

Course Creator

David M. Lutkemeier
David Lutkemeier holds a BA degree in psychology, a master’s degree in developmental psychology, and a doctorate degree from the University of Cincinnati in Special Education and Psychology. He is certified as a psychologist by the Arizona Board of Psychologist Examiners, as well as holding public school superintendent certification in Arizona and California. Dr. Lutkemeier has worked as an assistant professor at Arizona State University, a school psychologist, special education director, assistant superintendent, and superintendent in both Arizona and California. David, working as a consultant with a national curriculum management group (CMSi) has completed over two dozen comprehensive district-wide curriculum audits in 15 states over the past 20 years and has worked as a test developer for CE Learning Systems for the past ten years.

Recommended For:

Counselors, marriage and family therapists, psychologists and social workers. This course is appropriate for intermediate and above levels of knowledge.

Course Objectives:

After taking this course, you should be able to:

  1. Describe the pertinent factors identified in this article regarding increased risk of Opioid Related Adverse Events (ORAEs) among older adults.
  2. Examine the reported patterns of prescription opioid dose and their association with risk for ORAEs among older patients.
  3. Discuss those factors identified in this study that were associated with an increased risk for opioid-related adverse events in older patients.

Disclosure to Learners

Disclosure of Relevant Financial Relationships

CE Learning Systems adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Medical Education. Any individuals in a position to control the content of a CE activity – including faculty, planners, reviewers, or others ― are required to disclose all relevant financial relationships with ineligible entities (formerly known as commercial interests).

The following relevant financial relationships have been disclosed by this activity's planners, faculty, and the reviewer:

Planners and Reviewers

The planners of this activity have reported that they have no relevant financial relationships.

Commercial support

There is no commercial support for this distance-learning course.

Exam Questions

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Course Number 103399
1 CE credit hour
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  • Reading-Based Online
Exam Fee $5.97
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