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One Is Not Enough: Understanding and Modeling Polysubstance Use

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About the Course

This article reviews the current state of the field in understanding the behavioral and neural circuitry in the context of co-use with common pairings of alcohol, nicotine, cannabis, and other addictive substances. This course focuses heavily on the neurobiology of addiction.

This course is based on the reading-based online article, One Is Not Enough: Understanding and Modeling Polysubstance Use, created by Elizabeth A Crummy, PhD. et al. in 2020.

Publication Date:

Front. Neurosci., 16 June 2020 Jun 2020

Course Material Authors

Course Material Authors authored the material only, and were not involved in creating this CE course. They are identified here for your own evaluation of the relevancy of the material this course is based on.

Elizabeth A Crummy, PhD.

Dr. Crummy is a postdoctoral researcher at the Graduate Program in Neuroscience, University of Washington, Seattle, WA, United States, Center for Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA. Her research interests and projects include behavioral investigation of differences in substance use phenotypes between single vs. poly-drug use history in rat models, as well as elucidating the role of glutamatergic cortical projection neuron subtypes in behavioral outputs. She has had multiple works published in peer reviewed journals.

Timothy Joseph O'Neal, PhD (student)

Timothy is enrolled in the Graduate Program in Neuroscience, University of Washington, Seattle, WA. His research focuses on motivation, behavior, and decision-making. He has had multiple works published in peer reviewed journals.

Recommended For:

Counselors, marriage and family therapists, psychologists and social workers. This course is appropriate for all levels of knowledge.

Course Objectives:

After taking this course, you should be able to:

  1. Summarize existing literature on the behavioral and neural circuitry in the context of co-use with common pairings of alcohol, nicotine, cannabis, and other addictive substances.
  2. Outline effects of polydrug use on addictive behaviors.
  3. Review mechanisms of acute and long term action on the brain.

Disclosure to Learners

Disclosure of Relevant Financial Relationships

CE Learning Systems adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Medical Education. Any individuals in a position to control the content of a CE activity – including faculty, planners, reviewers, or others ― are required to disclose all relevant financial relationships with ineligible entities (formerly known as commercial interests).

The following relevant financial relationships have been disclosed by this activity's planners, faculty, and the reviewer:

Planners and Reviewers

The planners of this activity have reported that they have no relevant financial relationships.

Commercial support

There is no commercial support for this distance-learning course.

Exam Questions

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  • What do I have to do to complete the course?

    To complete the course, review the course objectives, then review the material, and then pass the exam with a score of 75% or greater and lastly complete an evaluation.

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Course Number 103482
2 CE credit hours
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  • Reading-Based Online
Exam Fee $11.94
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