This course is based on three NIDA Notes articles. NIDA Notes is a large collection of brief relevant articles focusing on current drug abuse treatment evidence.
Genetic Engineering Reveals Proteins’ Key Role in Sensitivity to Cocaine describes how genetic engineering strategies like those used at the California Institute of Technology to study nicotine addiction have helped other investigators identify a pair of proteins that seem to influence cocaine addiction.
Researchers Investigate Cocaine “Abstinence Syndrome” explains how researchers have focused on motivation as the centerpiece of the addiction puzzle based on the observation that in many addicted individuals, compulsive drug-seeking behavior overtakes the most fundamental motivators, including food and sex.
Sigma Antagonists: Potential Cocaine Medications With Novel Activity details how finds from a study strengthen speculation that drugs like rimcazole might help recovering individuals avoid temptations to relapse to cocaine.
All three articles are contained in one PDF.
This course is based on the reading-based online article, Cocaine Research Update: Collection X (NIDA Notes): Article 1: Genetic Engineering Reveals Proteins’ Key Role in Sensitivity to Cocaine; Article 2: Reseachers Investigate Cocaine “Abstinence Syndrome;” Article 3: Sigma Antagonists: Potential Cocaine Medications With Novel Activity created by Lori Whitten and Patrick Zickler
August 2005 and December 2004
Course Material Author
Lori Whitten and Patrick Zickler
Lori Whitten and Patrick Zickler are NIDA Notes staff writers.
Lori Whitten and Patrick Zickler authored the material only, and was not involved in creating this CE course. They are identified here for your own evaluation of the relevancy of the material this course is based on.
Dan Rebek, Ph.D.
This course is recommended for health care professionals, especially addiction counselors, psychologists, mental health counselors, social workers, and nurses who seek knowledge about how genetic engineering reveals proteins' key role in sensitivity to cocaine; how researchers investigate the cocaine "abstinence syndrome;" and how sigma antagonists are potential cocaine medications with novel activity.
After taking this course, you should be able to:
Explain how genetic engineering reveals proteins' key role in sensitivity to cocaine.
Describe the "abstinence syndrome" as it relates to cocaine.
Identify how coadministration of rimcazole with cocaine blocks locomotor stimulation in mice and how pretreatment with rimcazole analog SH3-28 decreases subjective effects of cocaine in rats.
Disclosure of Relevant Financial Relationships
Disclosure of Relevant Financial Relationships
CE Learning Systems, LLC is an independent provider of continuing medical education. CE Learning Systems, LLC has no proprietary or financial interest in medical or healthcare products over which the FDA (USA) or EMA (EU) has regulatory authority.
In accordance with our disclosure policies, CE Learning Systems, LLC is committed to ensuring balance, independence, objectivity, and scientific rigor for all accredited continuing education. These policies include assigning relevance to, and mitigating, all perceived or real conflicts of interest between any individual with control over the content and any ineligible company (commercial interest).
Any individual with control over accredited content, including planner, faculty, and reviewer, is required to globally disclose:
Individual relationship(s) or lack thereof, and its nature, with any/all ineligible company, and
any investigational, off-label, or non-FDA approved content or discussion
CE Learning Systems, LLC has reviewed these disclosures, assigned relevance based on the relationship and scope of content, and identified those with the potential to compromise the goals and educational integrity of the education. Relevant relationships, or lack thereof, are shared with the learner.
Education has been independently peer-reviewed to validate content, mitigate identified conflicts of interest, and ensure:
All recommendations involving clinical medicine is based on evidence that is accepted within the medical profession as adequate justification for their indications and contraindications in the care of patients.
All scientific research referred to, reported, or used in accredited continuing education in support or justification of a patient care recommendation conforms to the generally accepted standards of experimental design, data collection, and analysis.
Content is appropriate, fair and balanced, unbiased, referenced, and non-promotional.
The planners have reported the following: There are no relevant disclosures.
Course Material Author
The authors have disclosed any disclosures within the material.
Course Creator: Dan Rebek, Ph.D.
There are no relevant disclosures.
There is no commercial support for this distance-learning course.
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