Skip to main content

How Adaptation of the Brain to Alcohol Leads to Dependence: A Pharmacological Perspective

To help ensure your CEs are relevant to your practice, we regularly retire courses that are no longer current. This course has been retired. It is no longer available.

We add new courses all the time. Try these categories:

About the Course:

The development of alcohol dependence is posited to involve numerous changes in brain chemistry (i.e., neurotransmission) that lead to physiological signs of withdrawal upon abstinence from alcohol as well as promote vulnerability to relapse in dependent people. Studies of these neuroadaptive changes have been aided by the development of animal models of alcohol dependence, withdrawal, and relapse behavior. These animal models, as well as findings obtained in humans, have shed light on the effects that acute and chronic alcohol exposure have on signaling systems involving neurotransmitters as well as on other signaling molecules. Some of these systems are targets of currently available therapeutic agents for alcohol dependence. This publication discusses this field of study.

This course is based on the reading-based online article, How Adaptation of the Brain to Alcohol Leads to Dependence: A Pharmacological Perspective created by Peter Clapp, Ph.D.; Sanjiv V. Bhave, Ph.D.; and Paula L. Hoffman, Ph.D. in 2008.

Journal/Publisher:

National Institute on Alcohol Abuse and Alcoholism

Publication Date:

Alcohol Research and Health, Volume 21, Number 4, 2008

Course Material Author

Peter Clapp, Ph.D.; Sanjiv V. Bhave, Ph.D.; and Paula L. Hoffman, Ph.D.
Peter Clapp, Ph.D., is a postdoctoral fellow, Sanjiv V. Bhave, Ph.D., is a senior instructor, and Paula L. Hoffman, Ph.D., is a professor in the Department of Pharmacology, University of Colorado Denver School of Medicine, Aurora, Colorado.

Peter Clapp, Ph.D.; Sanjiv V. Bhave, Ph.D.; and Paula L. Hoffman, Ph.D. authored the material only, and was not involved in creating this CE course. They are identified here for your own evaluation of the relevancy of the material this course is based on.

Course Creator

Dan Rebek, Ph.D.

Recommended For:

This course is recommended for health care professionals, especially addiction counselors, psychologists, mental health counselors, social workers, and nurses who seek knowledge about how adaptation of the brain to alcohol leads to dependence. It is appropriate for intermediate to advanced levels of participants' knowledge.

Course Objectives:

After taking this course, you should be able to:

  1. Discuss the relationship of glutamate systems to alcohol dependence and the involvement of other brain-signaling systems such as serotonin, endogenous cannabinoids, and CREB protein.
  2. Describe animal models used to study neuroadaptation, and discuss signal transmission in the nervous system.
  3. Explain the relationship of alcohol dependence to the opiate systems, gamma-aminobutyric acid (GABA) systems, stress, and corticotrophin releasing factor (CRF).

Exam Questions

All exam questions for the course are visible on this page for members of Addiction Counselor CE.

Membership is free, and you can register today! You'll only pay when you're ready to purchase a course, or if you take advantage of the Unlimited Package.

If you're already a member, please sign in to see the exam questions for this and all other courses.

Discuss this course

When you're an Unlimited CE or Pay As You Go member you can discuss this course after you pass the exam.

Sign In or Register to get started.

FAQs

  • Is this course approved for my continuing education requirements?

    Yes, most likely. Look Up Your State Board for more detailed information. Logged-in site members will see the relevant approval information displayed in the Approvals tab for every course.

  • Do you have accommodations for my disability (ADA)?

    If you are having trouble using Addiction Counselor CE, please contact us! We would be happy to accommodate your needs right away, and your input will help us make Addiction Counselor CE more accessible for future users too.

  • How do I enroll in this course?

    Use the Enroll In This Course button and just follow the instructions! You don't pay anything until you're ready to take an exam.

  • What do I have to do to complete the course?

    To complete the course, review the course objectives, then review the material, and then pass the exam with a score of 75% or greater and lastly complete an evaluation.

  • How do I access the materials?

    Most of our courses are based on online articles available for free to the public. Some courses, such as those based on books, require that you purchase the material. Use the Materials tab above for more info. You don't need to enroll in the course to access materials, whether free or paid. So you always know what you're getting into before you commit to taking the exam.

  • How do I get my certificate?

    Your certificate(s) will be available to download or email immediately when you pass the course exam and complete the evaluation.

  • Can I contact you for more help?

    Yes! Use the Help widget at the bottom-right of the screen anywhere on Addiction Counselor CE to search our help docs, or to ask our support team for help. Unlike most of our competitors, Addiction Counselor CE has live US-based support reps to help you by email, chat, or phone.

Course Retired
Course Number 101620
3 CE credit hours
Sign in for credit hours relevant to your credentials.

  • Reading-Based Online
Exam Fee $17.91
There's no exam fee with an Unlimited CE membership! Read More

No Cost Materials

1150 members have taken this course

Try a free CE course.

Get started by trying a free course of your choice. No payment info required!

Sign Up Free

View all free trial courses

Happy therapist using Addiction Counselor CE